Article
HLA-B*3531, a hybrid of B35 and B61, implications for diagnostic approaches to alleles with complex ancestral compositions.
Tissue antigens - 1 Jul 2002
Elsner H-A, Himmel A, Steitz M, Hammer P, Schmitz G, Ballas M, Blasczyk R
Abstract excerpt
The serological characterization of allelic variants that have been generated by large-scale interallelic recombination events indicates which residues may be involved in the formation of epitopes crucial for serological recognition. The allelic product of HLA-B*3531 is composed of B35 in its alpha1 domain and of B61(40) in its alpha2 domain. Both specificities are only weakly detectable with available sera....
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