Article
Arteriosclerosis in rat aortic allografts: early changes in endothelial integrity and smooth muscle phenotype.
Transplantation - 15 Jul 2000
Bojakowski K, Religa P, Bojakowska M, Hedin U, Gaciong Z, Thyberg J
Abstract excerpt
BACKGROUND: Transplant arteriosclerosis remains a limiting factor for the long-term survival of transplanted organs and effective treatment is lacking. A rat model of aortic allografts was used to analyze this process by electron microscopy and further characterize the phenotypic properties of the cells involved. METHODS: A segment of abdominal aorta was transplanted orthotopically from Fischer to Lewis rats. The...
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