Article
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.
Molecular carcinogenesis - 1 Jan 1992
Larcher F, Bauluz C, Díaz-Guerra M, Quintanilla M, Conti C J, Ballestín C, Jorcano J L
Abstract excerpt
Keratins have been demonstrated to be suitable markers of changes taking place during epithelial neoplasia. Therefore, we analyzed 18 mouse skin tumors (nine papillomas and nine squamous cell carcinomas), induced either by two-stage carcinogenesis with 7,12-dimethylbenz[a]anthracene(DMBA)/12-O-te...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Blotting, Northern
- Carcinoma, Squamous Cell
- Electrophoresis, Polyacrylamide Gel
- Epithelium
- Female
- Fluorescent Antibody Technique
- Gene Expression
- Genes, ras
- Immunoenzyme Techniques
- Keratins
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mutation
- Papilloma
- RNA