Article
Relationship of large and small CD3- CD56+ lymphocytes mediating NK-associated activities.
Journal of leukocyte biology - 1 Sept 1992
Ortaldo J R, Winkler-Pickett R, Kopp W, Kawasaki A, Nagashima K, Okumura K, Yagita H, Bach F H
Abstract excerpt
We have defined a population of CD3-, CD56+ small lymphocytes (SLs) that exhibit the same phenotype and lytic capacity as natural killer (NK) cells. NK cells characteristically express the surface markers CD16 and CD56, mediate non-major histocompatibility complex (MHC)-restricted lysis, and have been equated with CD3- large granular lymphocytes (LGLs). In the present study we extended the observation that CD3-,...
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