Article
Relationship of large and small CD3- CD56+ lymphocytes mediating NK-associated activities.
Journal of leukocyte biology - 1 Sept 1992
Ortaldo J R, Winkler-Pickett R, Kopp W, Kawasaki A, Nagashima K, Okumura K, Yagita H, Bach F H
Abstract excerpt
We have defined a population of CD3-, CD56+ small lymphocytes (SLs) that exhibit the same phenotype and lytic capacity as natural killer (NK) cells. NK cells characteristically express the surface markers CD16 and CD56, mediate non-major histocompatibility complex (MHC)-restricted lysis, and have...
Topics
- Antibody-Dependent Cell Cytotoxicity
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- CD56 Antigen
- Humans
- Interferon-gamma
- Interleukin-2
- Killer Cells, Natural
- Lymphocyte Activation
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocyte Subsets