Article
Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis.
The Journal of allergy and clinical immunology - 1 Aug 1992
van Reijsen F C, Bruijnzeel-Koomen C A, Kalthoff F S, Maggi E, Romagnani S, Westland J K, Mudde G C
Abstract excerpt
T-cell lines have been derived from aeroallergen-induced eczematous patch test sites of patients with atopic dermatitis (AD). Biopsy specimens were obtained 24 hours after allergen application to the skin, and only in vivo-activated T cells were propagated. From one patient, the T-cell lines were...
Topics
- Allergens
- Antigens
- B-Lymphocytes
- Cell Division
- Clone Cells
- Cytokines
- Dermatitis, Atopic
- Epitopes
- Humans
- Immunoglobulin E
- Interleukin-2
- Phenotype
