Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM.

doi:10.1083/jcb.118.4.937

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Article

Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM.

The Journal of cell biology - 1 Aug 1992

Rao Y, Wu X F, Gariepy J, Rutishauser U, Siu C H

Abstract excerpt

The neural cell adhesion molecule NCAM is capable of mediating cell-cell adhesion via homophilic interactions. In this study, three strategies have been combined to identify regions of NCAM that participate directly in NCAM-NCAM binding: analysis of domain deletion mutations, mapping of epitopes...

Topics

Amino Acid Sequence
Animals
Base Sequence
Binding Sites
Brain
Cell Adhesion
Cell Adhesion Molecules, Neuronal
Cell Aggregation
Cell Line, Transformed
Chick Embryo
Epitopes
L Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Molecular Sequence Data

Mutation

Oligopeptides

Retina

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 1380002
DOI: 10.1083/jcb.118.4.937
PMCID: PMC2289564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1380002-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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