Article
Neural cell adhesion molecule (NCAM) isoform expression is associated with neuroblastoma differentiation status
22 Jan 2008
Abstract excerpt
BACKGROUND: NCAM is a member of the immunoglobulin superfamily of cell adhesion molecules. While highly expressed on neuroblastoma cells, the relative contribution of the three major NCAM isoforms (120, 140, and 180 kDa) to neuroblastoma biology has not been investigated. METHODS: NCAM protein expression was measured in a neuroblastic tumor tissue microarray (N = 185) by immunohistochemistry. Relative expression...