Article
In vitro and in vivo mutagenicity studies on sporidesmin, the toxin associated with facial eczema in ruminants.
Mutation research - 1 Aug 1992
Ferguson L R, Berriman J, Pearson A, Munday R, Fowke E A, Towers N R
Abstract excerpt
Sporidesmin, a fungal toxin with widespread distribution within New Zealand, is thought to exert toxic effects through oxidative damage. The purified chemical was tested for its ability to cause point mutations in four strains of Salmonella typhimurium (TA98, TA100, TA102 and TA1537), in the pres...
Topics
- Animals
- Cell Survival
- Cells, Cultured
- Chromatids
- Chromosome Aberrations
- Cricetinae
- Cricetulus
- Eczema
- Micronuclei, Chromosome-Defective
- Mutagenesis
- Mutagenicity Tests
- Mutation
- Salmonella typhimurium
- Sheep
- Sheep Diseases
- Sporidesmins