Article
Human vaccination with Escherichia coli J5 mutant induces cross-reactive bactericidal antibody against Neisseria gonorrhoeae lipooligosaccharide.
The Journal of infectious diseases - 1 Aug 1992
Dale P A, McQuillen D P, Gulati S, Rice P A
Abstract excerpt
The lipopolysaccharides of enteric gram-negative bacteria and the lipooligosaccharides (LOS) of Neisseria gonorrhoeae may share antigenic determinants that are targets of bactericidal antibody. Natural (disseminated) infection with a serum-resistant gonococcal strain and immunization with Escherichia coli J5 stimulated bactericidal IgG anti-LOS antibodies that recognize different serum-resistant gonococcal LOS...
Topics
- Antibodies, Bacterial
- Antigens, Bacterial
- Blotting, Western
- Cross Reactions
- Epitopes
- Escherichia coli
- Humans
- Lipopolysaccharides
- Liposomes
- Mutation
- Neisseria gonorrhoeae
