Article
Highly ConservedNeisseria meningitidisInner‐Core Lipopolysaccharide Epitope Confers Protection against Experimental Meningococcal Bacteremia
15 Apr 2003
Abstract excerpt
Inner-core lipopolysaccharide (LPS) from Neisseria meningitidis is under investigation as a vaccine for prevention of meningococcal disease caused by N. meningitidis serogroup B (NmB). We investigated the functional activity of murine monoclonal antibody (MAb) B5 that recognizes a highly conserved (galE) LPS epitope. Three patterns of MAb reactivity were observed in N. meningitidis by Western blot, depending on...
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