Localization and characterization of serologic epitopes on HLA-A2.

doi:10.1016/0198-8859(92)90070-4

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Article

Localization and characterization of serologic epitopes on HLA-A2.

Human immunology - 1 Mar 1992

Hogan K T, Brown S L

Abstract excerpt

A panel of cells expressing 68 different mutant HLA-A2 genes was generated by site-directed mutagenesis and DNA-mediated gene transfer in order to define the regions of class I MHC molecules that contribute to the epitopes recognized by mAb. Each of the variant HLA-A2 molecules differed from HLA-...

Topics

Cross Reactions
Epitopes
HLA-A2 Antigen
Humans
Mutation
Structure-Activity Relationship
Transfection

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