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Article

Streptomycin biosynthesis and its regulation in Streptomycetes.

Gene - 15 Jun 1992

Distler J, Mansouri K, Mayer G, Stockmann M, Piepersberg W

Abstract excerpt

New insights into the gene orders, structures, evolution, and functions of streptomycin (Sm) biosynthetic genes (str) were gained via hybridization studies, determination of nucleotide sequences, and measurement of expression in the str gene clusters of Streptomyces griseus and S. glaucescens. Both str clusters showed considerable divergence in macro and micro structure. Genes putatively involved in pathways...

Topics

Bacterial Proteins
Dihydrostreptomycin Sulfate
Multigene Family
Phenotype
Phosphoric Monoester Hydrolases
Phosphorylation
Regulatory Sequences, Nucleic Acid
Sequence Homology, Nucleic Acid
Streptomyces
Streptomyces griseus
Streptomycin

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Identifiers

PMID: 1377151
DOI: 10.1016/0378-1119(92)90547-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1377151-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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