Article
A eukaryotic gene encoding an endonuclease that specifically repairs DNA damaged by ultraviolet light.
The EMBO journal - 15 May 1995
Yajima H, Takao M, Yasuhira S, Zhao J H, Ishii C, Inoue H, Yasui A
Abstract excerpt
Many eukaryotic organisms, including humans, remove ultraviolet (UV) damage from their genomes by the nucleotide excision repair pathway, which requires more than 10 separate protein factors. However, no nucleotide excision repair pathway has been found in the filamentous fungus Neurospora crassa. We have isolated a new eukaryotic DNA repair gene from N.crassa by its ability to complement UV-sensitive Escherichia...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA Damage
- DNA Repair
- Endonucleases
- Escherichia coli
- Eukaryotic Cells
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test