Isolation and characterization of temperature-sensitive mutants of Streptomyces coelicolor A3(2) blocked in macromolecular synthesis.

doi:10.1099/00221287-138-3-579

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Article

Isolation and characterization of temperature-sensitive mutants of Streptomyces coelicolor A3(2) blocked in macromolecular synthesis.

Journal of general microbiology - 1 Mar 1992

Flett F, Platt J, Oliver S G

Abstract excerpt

A collection of temperature-sensitive mutants of Streptomyces coelicolor A3(2) was isolated. The majority of the mutants showed an osmotically remedial phenotype. Mutants defective in macromolecular synthesis were identified and characterized further. Four mutants were found in which DNA replicat...

Topics

Cell Division
Culture Media
DNA Replication
Gene Expression Regulation, Bacterial
Hot Temperature
Mutation
Phenotype
Proteins
RNA
Streptomyces
Suppression, Genetic

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