Article
Two genes involved in the phase-variable phi C31 resistance mechanism of Streptomyces coelicolor A3(2).
Journal of bacteriology - 1 Aug 1995
Bedford D J, Laity C, Buttner M J
Abstract excerpt
The phage growth limitation (Pgl) system of Streptomyces coelicolor confers resistance to phi C31 and its homoimmune phages. The positions of the pgl genes within a 16-kb clone of S. coelicolor DNA were defined by subcloning, insertional inactivation, and deletion mapping. Nucleotide sequencing and functional analysis identified two genes, pglY and pglZ, required for the Pgl+ (phage-resistant) phenotype. pglY and...
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