Article
Sequence variation in the tripeptide repeats and T cell epitopes in P190 (MSA-1) of Plasmodium falciparum from field isolates.
Molecular and biochemical parasitology - 1 Mar 1992
Jongwutiwes S, Tanabe K, Nakazawa S, Yanagi T, Kanbara H
Abstract excerpt
The N-terminal part of p190, the precursor to the major merozoite surface antigens of Plasmodium falciparum, contains the T and B cell epitopes and tripeptide repeats. The p190 gene exhibits allelic dimorphism, but the tripeptide repeat-encoding region is the only exception to the dimorphic variations of the gene. To date, sequences available to document variations in the epitopes are very limited. Thus, in this...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Antigens, Surface
- Base Sequence
- Epitopes
- Genetic Variation
- Merozoite Surface Protein 1
- Molecular Sequence Data
- Oligopeptides
- Plasmodium falciparum