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Article

Genetic variation in the dimorphic regions of RAP-1 genes and rap-1 loci of Babesia bigemina.

Molecular and biochemical parasitology - 15 Dec 1997

Hötzel I, Suarez C E, McElwain T F, Palmer G H

Abstract excerpt

The rhoptry-associated protein-1 (RAP-1) of Babesia bigemina induces protective immune responses in cattle. RAP-1 has two regions of sequence dimorphism at the carboxy and amino terminal ends, respectively. Neutralization-sensitive, surface-exposed B-cell epitopes are present in the amino terminal variant type 1 (NT-1), and CD4+ T-cell epitopes in the carboxy terminal variant type 1 (CT-1). Importantly,...

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PMID: 9476795
DOI: 10.1016/s0166-6851(97)00182-5

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