Article
Stability of anticancer activity induced by cellular differentiation.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1990
Maercklein P B, Estervig D N, Scott R E
Abstract excerpt
Human and murine cells can express anticancer activity which we define as any biologic process that can prevent or inhibit the expression of the transformed phenotype. The existence of anticancer activities has been demonstrated by many systems, including the fusion of normal cells with tumorigenic cells and the implantation of cancer cells into specific embryonic sites. Furthermore, cellular differentiation has...
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