Article
Characterization of the antigenic and adhesive properties of FaeG, the major subunit of K88 fimbriae.
Molecular microbiology - 1 Jan 1992
Bakker D, Willemsen P T, Simons L H, van Zijderveld F G, de Graaf F K
Abstract excerpt
The two K88 serotypes, K88ab and K88ac, differ in terms of antigenic and adhesive properties. The structural determinants of the serotype-specific epitopes and the identify of the amino acid residues involved in fimbriae-receptor interaction were studied by the construction and analysis of K88 hybrid proteins in which various parts of the K88ab and K88ac fimbrial subunit FaeG were exchanged, and by in vitro...
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Antigens, Bacterial
- Antigens, Surface
- Base Sequence
- Epitopes
- Escherichia coli
- Escherichia coli Proteins
- Fimbriae Proteins
- Fimbriae, Bacterial
- Hemagglutination