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Article

Porphyromonas gingivalis FimA fimbriae: fimbrial assembly by fimA alone in the fim gene cluster and differential antigenicity among fimA genotypes.

PloS one - 1 Jan 2012

Nagano Keiji, Hasegawa Yoshiaki, Abiko Yuki, Yoshida Yasuo, Murakami Yukitaka, Yoshimura Fuminobu

Abstract excerpt

The periodontal pathogen Porphyromonas gingivalis colonizes largely through FimA fimbriae, composed of polymerized FimA encoded by fimA. fimA exists as a single copy within the fim gene cluster (fim cluster), which consists of seven genes: fimX, pgmA and fimA-E. Using an expression vector, fimA alone was inserted into a mutant from which the whole fim cluster was deleted, and the resultant complement exhibited a...

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Identifiers

PMID: 22970139
DOI: 10.1371/journal.pone.0043722
PMCID: PMC3436787

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Source receipt: pubmed, retrieved 7 Sept 2026.

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