Article
Two monoclonal antibodies recognizing different epitopes on rat cytochrome IIB1 react with human IIE1.
Molecular pharmacology - 1 Jan 1992
Wrighton S A, Vandenbranden M, Becker G W, Black S D, Thomas P E
Abstract excerpt
To identify human cytochromes P450 (P450) in the CYP2B subfamily, 14 human liver microsomal samples were screened by immunoblots developed with monoclonal antibodies that recognized seven distinct epitopes on rat IIB1. Two of these antibodies recognized a protein in all of the samples. This protein was termed P450BE. Using video-imaging densitometry, the levels of P450BE were determined and compared with levels...
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