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Article

Cloning and nucleotide sequencing of the antitumor antibiotic C-1027 apoprotein gene.

Bioscience, biotechnology, and biochemistry - 1 Oct 1992

Sakata N, Ikeno S, Hori M, Hamada M, Otani T

Abstract excerpt

The apoprotein gene for a chromoprotein antitumor antibiotic, C-1027, was cloned from the producer strain, Streptomyces globisporus C-1027, and sequenced. The process verified that; (1) the sequence included the entire structural gene directing a precursor of the apoprotein (pre-apoprotein having Met1---Ala33 leader peptide ahead of the apoprotein) and flanking regions, (2) the amino acid sequence of the...

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PMID: 1369059
DOI: 10.1271/bbb.56.1592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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