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Article

Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from Streptomyces capreolus.

European journal of biochemistry - 1 Nov 2002

Saugar Irene, Sanz Eloísa, Rubio Miguel Angel, Espinosa Juan Carlos, Jiménez Antonio

Abstract excerpt

A novel cosmid (pABC6.5) whose DNA insert from Streptomyces capreolus, the A201A antibiotic producer, overlaps the inserts of the previously reported pCAR11 and pCAR13 cosmids, has been isolated. These two latter cosmids were known to contain the aminonucleoside antibiotic A201A resistance determinants ard2 and ard1, respectively. Together, these three cosmids have permitted the identification of a DNA stretch of...

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PMID: 12423351
DOI: 10.1046/j.1432-1033.2002.03258.x

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