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Article

Influence of ACE (I/D) and G460W polymorphism of alpha-adducin in autosomal dominant polycystic kidney disease.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2003

Persu Alexandre, El-Khattabi Ouarda, Messiaen Thierry, Pirson Yves, Chauveau Dominique, Devuyst Olivier

Abstract excerpt

BACKGROUND: The deleterious effect of the DD genotype of ACE in autosomal dominant polycystic kidney disease (ADPKD) remains controversial. Small sample size, population admixture and lack of consideration of parameters modulating the effects of ACE genotype, such as gender or alpha-adducin (ADD)...

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Source

Identifiers

PMID: 13679477
DOI: 10.1093/ndt/gfg292

Genes

ACE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-13679477-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Influence of ACE (I/D) and G460W polymorphism of alpha-adducin in autosomal dominant polycystic kidney disease.PMID 13679477Read ↗

Influence of the ACE gene polymorphism in the progression of renal failure in autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Effect of ACE gene polymorphism on age at renal death in polycystic kidney disease in Japan.Semantic proximity Read ↗

Influence of the alpha-adducin and ACE gene polymorphism on the progression of autosomal-dominant polycystic kidney disease.Semantic proximity Read ↗

Influence of ACE I/D gene polymorphism in the progression of renal failure in autosomal dominant polycystic kidney disease: a meta-analysis.Semantic proximity Read ↗

Role of the alpha-adducin genotype on renal disease progression.Semantic proximity Read ↗

The ACE insertion/deletion polymorphism has no influence on progression of renal function loss in autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Association of the ACE gene polymorphism with the progression of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

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Impact of ACE I/D gene polymorphism on congenital renal malformations.Semantic proximity Read ↗

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