Article
Role of the alpha-adducin genotype on renal disease progression.
Kidney international - 1 Apr 2002
Nicod Jérôme, Frey Brigitte M, Frey Felix J, Ferrari Paolo
Abstract excerpt
BACKGROUND: A genetic susceptibility to hypertension may predispose to the development of end-stage renal disease (ESRD) and promote a more rapid loss of renal function in patients with renal diseases. The alpha-adducin (ADD) gene, alone or in combination with the angiotensinogen (AGT) and the angiotensin-converting enzyme (ACE), is a candidate for abnormal blood pressure regulation and thus for increased...
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