Article
Nuclear localization and transcriptional repression are confined to separable domains in the circadian protein CRYPTOCHROME.
Current biology : CB - 16 Sept 2003
Zhu Haisun, Conte Francesca, Green Carla B
Abstract excerpt
Circadian rhythms are driven by molecular clocks composed of interlocking transcription/translation feedback loops. CRYPTOCHROME (CRY) proteins are critical components of these clocks and repress the activity of the transcription factor heterodimer CLOCK/BMAL1. Unlike the homologous DNA repair en...
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