Article
Human DNA polymorphisms and methods of analysis.
Current opinion in biotechnology - 1 Dec 1990
Weber J L
Abstract excerpt
The current predominant method of analyzing base substitution polymorphisms, RFLP analysis, is likely to be gradually supplanted by methods based on PCR because of the improved sensitivity and genotyping rate. The most promising PCR methods for analysis appear to be allele-specific PCR and single-stranded conformational analysis. The single-stranded conformation approach has already been applied to the scanning...
Topics
- DNA
- Genome, Human
- Genotype
- Humans
- Polymorphism, Genetic