Article
Sequence variation in the Fanconi anemia gene FAA.
Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 1997
Levran O, Erlich T, Magdalena N, Gregory J J, Batish S D, Verlander P C, Auerbach A D
Abstract excerpt
Fanconi anemia (FA) is a genetically heterogeneous autosomal recessive syndrome associated with chromosomal instability, hypersensitivity to DNA crosslinking agents, and predisposition to malignancy. The gene for FA complementation group A (FAA) recently has been cloned. The cDNA is predicted to...
Topics
- Cell Cycle Proteins
- Consensus Sequence
- DNA-Binding Proteins
- Fanconi Anemia
- Fanconi Anemia Complementation Group Proteins
- Humans
- Mutation
- Nuclear Proteins
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Proteins
- Sequence Deletion