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Article

Comparative analysis of human DNA variations by fluorescence-based sequencing of PCR products.

Genomics - 1 Sept 1994

Kwok P Y, Carlson C, Yager T D, Ankener W, Nickerson D A

Abstract excerpt

Automated, direct cycle sequencing of purified double-stranded PCR products using Taq polymerase and fluorescently labeled dideoxynucleotide terminators provides a robust and highly reproducible method for identifying DNA sequence variations in sequence-tagged sites. We describe a simple and sens...

Topics

Alleles
Automation
Base Sequence
DNA
DNA-Directed DNA Polymerase
Fluorometry
Gene Frequency
Genetic Variation
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Reproducibility of Results

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, DNA

Taq Polymerase

Source

Identifiers

PMID: 7829062
DOI: 10.1006/geno.1994.1469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7829062-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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