Article
Beijerinckia indica var. penicillanicum penicillin V acylase: enhanced enzyme production by catabolite repression-resistant mutant and effect of solvents on enzyme activity.
Journal of industrial microbiology - 1 Apr 1991
Ambedkar S S, Deshpande B S, Sudhakaran V K, Shewale J G
Abstract excerpt
Beijerinckia indica var. penicillanicum mutant UREMS-5, producing 168% more penicillin V acylase, was obtained by successive treatment with UV, gamma-irradiation and ethylmethane sulfonate. Penicillin V acylase production by the mutant strain was resistant to catabolite repression by glucose. Incorporation of glucose, sodium glutamate and vegetable oils in the medium enhanced enzyme production. The maximum...
Topics
- Carbon Tetrachloride
- Cell Membrane Permeability
- Chloroform
- Culture Media
- Ethyl Methanesulfonate
- Fermentation
- Gamma Rays
- Glucose
- Hydrolysis
- Methylene Chloride
- Mutation