Article
Carbon catabolite repression can account for the temporal pattern of expression of a penicillin biosynthetic gene in Aspergillus nidulans.
Molecular microbiology - 1 Jun 1992
Espeso E A, Peñalva M A
Abstract excerpt
Aspergillus nidulans synthesizes penicillins as secondary metabolites when grown under certain culture conditions. Broths containing carbon (C) sources that give rise to carbon catabolite repression (CCR) support a much lower antibiotic yield than broths with non-repressing C sources. Steady-stat...
Topics
- Aspergillus nidulans
- Carbon
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Regulator
- Mutation
- Oxidoreductases
- Penicillins
- RNA, Fungal
- Transcription, Genetic
