Article
Hidden amyloidoses.
Experimental and clinical immunogenetics - 1 Jan 1992
Diringer H
Abstract excerpt
The pathogenesis as well as the genetic disposition to develop clinical symptoms in transmissible spongiform encephalopathies (e.g. Creutzfeldt-Jakob disease, scrapie, bovine spongiform encephalopathy) relate these diseases to classical noninfectious amyloidoses (familial amyloidotic polyneuropathy as an example) and to Alzheimer's disease. This is not obvious to the nonexpert at first glance. This communication...
Topics
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- Amyloidosis
- Animals
- Brain
- Cricetinae
- Humans
- Mice
- Mice, Inbred C57BL
- Models, Biological
- Mutation
- Nerve Tissue Proteins