Article
Intracellular glutathione and its metabolizing enzyme activities in a metastatic variant melanoma cell line.
Melanoma research - 1 Dec 1992
Chakraborty A K, Ueda M, Mishima Y, Ichihashi M
Abstract excerpt
Levels of glutathione peroxidase (GSH-PX), glutathione-S-transferase (GST), gamma-glutamyl transpeptidase (gamma GTP) and glutathione reductase (GR) activities in the B16-F10 metastatic melanoma cell line are higher than those in non-metastatic B-16 murine melanoma cells. An inverse relationship was observed between the level of reduced glutathione (GSH) and metastatic capacity. Interferon (IFN), an antitumour...
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