Article
Intracellular glutathione and its metabolizing enzyme activities in a metastatic variant melanoma cell line.
Melanoma research - 1 Dec 1992
Chakraborty A K, Ueda M, Mishima Y, Ichihashi M
Abstract excerpt
Levels of glutathione peroxidase (GSH-PX), glutathione-S-transferase (GST), gamma-glutamyl transpeptidase (gamma GTP) and glutathione reductase (GR) activities in the B16-F10 metastatic melanoma cell line are higher than those in non-metastatic B-16 murine melanoma cells. An inverse relationship was observed between the level of reduced glutathione (GSH) and metastatic capacity. Interferon (IFN), an antitumour...
Topics
- Animals
- Cell Division
- Cell Line
- Genetic Variation
- Glutathione
- Glutathione Disulfide
- Glutathione Peroxidase
- Glutathione Reductase
- Glutathione Transferase
- Interferon Type I
- Melanoma, Experimental