Article
DNA repair pathways and human metastatic malignant melanoma.
Current molecular medicine - 1 Jun 2010
Sarasin A, Dessen P
Abstract excerpt
Melanoma causes a considerable public health burden because of its dramatic rise in incidence worldwide since the mid-1960s and because the metastatic disease remains incurable, has a short median survival and is characterized by resistance to almost all classes of cytotoxic agents. DNA repair pathways are multiple and are able to repair, usually in an error-free manner, all kinds of DNA damage induced by...
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