Article
Interaction of two variable proteins (PilE and PilC) required for pilus-mediated adherence of Neisseria gonorrhoeae to human epithelial cells.
Molecular microbiology - 1 Nov 1992
Rudel T, van Putten J P, Gibbs C P, Haas R, Meyer T F
Abstract excerpt
Pili confer the initial ability of Neisseria gonorrhoeae to bind to epithelial cells. Pilin (PilE), the major pilus subunit, and a minor protein termed PilC, reportedly essential for pilus biogenesis, undergo intra-strain phase and structural variation. We demonstrate here that at least two different adherence properties are associated with the gonococcal pili: one is specific for erythrocytes, which is virtually...
Topics
- Amino Acid Sequence
- Bacterial Adhesion
- Bacterial Proteins
- Base Sequence
- Cells, Cultured
- Consensus Sequence
- Epithelium
- Fimbriae Proteins
- Fimbriae, Bacterial
- Genes, Bacterial
- Genetic Complementation Test