Article
Neisseria gonorrhoeae PilC expression provides a selective mechanism for structural diversity of pili.
Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 1992
Jonsson A B, Pfeifer J, Normark S
Abstract excerpt
Pili of Neisseria gonorrhoeae undergo both phase and structural variation. Phase variation of gonococcal pili can be caused by a RecA-independent on/off switch in PilC, a protein involved in pilus biogenesis. We show here that spontaneous nonpiliated PilC- derivatives as well as PilC- insertional mutants have also acquired sequence alterations in pilE relative to the pilE gene of the piliated MS11mk(P+)-u parent,...
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