Article
Role of pili and the phase-variable PilC protein in natural competence for transformation of Neisseria gonorrhoeae.
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 1995
Rudel T, Facius D, Barten R, Scheuerpflug I, Nonnenmacher E, Meyer T F
Abstract excerpt
The Gram-negative bacterial pathogen Neisseria gonorrhoeae is naturally competent for transformation with species-related DNA. We show here that two phase-variable pilus-associated proteins, the major pilus subunit (pilin, or PilE) and PilC, a factor known to function in the assembly and adherence of gonococcal pili, are essential for transformation competence. The PilE and PilC proteins are necessary for the...
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