Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

X-linked lymphoproliferative disease: prenatal detection of an unaffected histocompatible male.

Clinical genetics - 1 Aug 1992

Mulley J C, Turner A M, Gedeon A K, Berdoukas V A, Huang T H, Ledbetter D H, Grierson H, Purtilo D T

Abstract excerpt

Chorionic Villous Biopsy (CVS) for diagnosis of XLP was undertaken at 10 weeks gestation in an obligate carrier. The fetus was found to be male by cytogenetic analysis. XLP (Xq25-q26) is closely linked to the RFLP markers DXS10, DXS37 and DXS42, but only DXS10 (distal to XLP) was informative for prenatal diagnosis in this family. RFLP analysis using this marker gave a 7% risk that the fetus was affected, based on...

Topics

Child, Preschool
Chorionic Villi Sampling
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Lymphoproliferative Disorders
Male
Pedigree
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Pregnancy

Recombination, Genetic

Sex Chromosome Aberrations

X Chromosome

Source

Identifiers

PMID: 1358486
DOI: 10.1111/j.1399-0004.1992.tb03143.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1358486-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

X-linked lymphoproliferative disease: prenatal detection of an unaffected histocompatible male.PMID 1358486Read ↗

X-linked lymphoproliferative disease. Detection of a paternally inherited mutation in a German family using haplotype analysis.Semantic proximity Read ↗

Methods of detection of new families with X-linked lymphoproliferative disease.Semantic proximity Read ↗

X-linked lymphoproliferative disease: twenty-five years after the discovery.Semantic proximity Read ↗

Evaluation of families wherein a single male manifests a phenotype of X-linked lymphoproliferative disease (XLP).Semantic proximity Read ↗

Deletion (X)(q26.1-->q28) in a proband and her mother: molecular characterization and phenotypic-karyotypic deductions.Semantic proximity Read ↗

[X-chromosome recessive lymphoproliferative disease (XLP): molecular genetic studies].Semantic proximity Read ↗

X linked fatal infantile cardiomyopathy maps to Xq28 and is possibly allelic to Barth syndrome.Semantic proximity Read ↗

Prenatal diagnosis of X-linked hypohidrotic ectodermal dysplasia by linkage analysis.Semantic proximity Read ↗

Fabry disease: molecular carrier detection and prenatal diagnosis by analysis of closely linked polymorphisms at Xq22.1.Semantic proximity Read ↗

DNA-based genetic testing in fifty fragile X families.Semantic proximity Read ↗

Gonadal mosaicism in a family with adrenoleukodystrophy: molecular diagnosis of carrier status among daughters of a gonadal mosaic when direct detection of the mutation is not possible.Semantic proximity Read ↗

Immunoglobulin class and subclass deficiencies prior to Epstein-Barr virus infection in males with X-linked lymphoproliferative disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.