Article
[X-chromosome recessive lymphoproliferative disease (XLP): molecular genetic studies].
Klinische Padiatrie - 1 Jan 2000
Schuster V, Grimm T, Kress W, Seidenspinner S, Belohradsky B H, Müller P, Kreth H W
Abstract excerpt
X-linked lymphoproliferative disease (XLP) is a rare worldwide occurring inherited immunodeficiency which is triggered by Epstein-Barr virus infection. Clinical phenotypes in 21 affected males from 5 German families with XLP ranged from severe and fatal infectious mononucleosis (57%) to acquired...
Topics
- Child
- Child, Preschool
- Chromosome Mapping
- DNA Probes
- Female
- Genes, Recessive
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Markers
- Haplotypes
- Herpesvirus 4, Human
- Humans
- Infectious Mononucleosis
- Lymphoproliferative Disorders
- Male
- Pedigree
- Phenotype
- Sex Chromosome Aberrations