Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunoglobulin class and subclass deficiencies prior to Epstein-Barr virus infection in males with X-linked lymphoproliferative disease.

American journal of medical genetics - 1 Sept 1991

Grierson H L, Skare J, Hawk J, Pauza M, Purtilo D T

Abstract excerpt

Patients with X-linked lymphoproliferative (XLP) disease are characterized by extreme vulnerability to Epstein-Barr virus (EBV). Following infection with EBV, affected males develop fatal infectious mononucleosis (IM), hypogammaglobulinemia (H), or non-Hodgkin's lymphoma (NHL). In addition, hyper IgM, red cell aplasia, necrotizing lymphoid vasculitis (NLV), and aplastic anemia occur rarely. The recent use of DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Linkage
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

Share to Immunoglobulins

Share to Immunologic Deficiency Syndromes

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to X Chromosome

Source

Identifiers

PMID: 1683154
DOI: 10.1002/ajmg.1320400309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunoglobulin class and subclass deficiencies prior to Epstein-Barr virus infection in males with X-linked lymphoproliferative disease.PMID 1683154Read ↗

Evaluation of families wherein a single male manifests a phenotype of X-linked lymphoproliferative disease (XLP).Semantic proximity Read ↗

Methods of detection of new families with X-linked lymphoproliferative disease.Semantic proximity Read ↗

[X-chromosome recessive lymphoproliferative disease (XLP): molecular genetic studies].Semantic proximity Read ↗

Correlation of mutations of the SH2D1A gene and epstein-barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease.Semantic proximity Read ↗

Frequent mutations in SH2D1A (XLP) in males presenting with high-grade mature B-cell neoplasms.Semantic proximity Read ↗

Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome.Semantic proximity Read ↗

X-linked lymphoproliferative disease: twenty-five years after the discovery.Semantic proximity Read ↗

Clinical spectrum of X-linked hyper-IgM syndrome.Semantic proximity Read ↗

Mutations of the CD40 ligand gene and its effect on CD40 ligand expression in patients with X-linked hyper IgM syndrome.Semantic proximity Read ↗

Epstein--Barr Virus-Negative Boys With Non-Hodgkin Lymphoma Are Mutated in the Sh2D1A Gene, as Are Patients With X-Linked Lymphoproliferative Disease (XLP)Semantic proximity Read ↗

CD40 ligand expression deficiency in a female carrier of the X-linked hyper-IgM syndrome as a result of X chromosome lyonization.Semantic proximity Read ↗

Enteroviral meningoencephalitis as a complication of X-linked hyper IgM syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.