Article
Evaluation of families wherein a single male manifests a phenotype of X-linked lymphoproliferative disease (XLP).
American journal of medical genetics - 15 Sept 1993
Grierson H L, Skare J, Church J, Silberman T, Davis J R, Kobrinsky N, McGregor R, Israels S, McCarty J, Andrews L G
Abstract excerpt
The Epstein-Barr virus (EBV)-induced diseases of males with X-linked lymphoproliferative disease (XLP) include fatal infectious mononucleosis (IM), non-Hodgkin lymphoma (ML), agammaglobulinemia, and aplastic anemia. These phenotypes also occur as sporadic cases in families, and EBV seronegative m...
Topics
- Adolescent
- Adult
- Cell Line
- Child
- Child, Preschool
- Female
- Genetic Carrier Screening
- Herpesvirus 4, Human
- Humans
- Infant
- Lymphoproliferative Disorders
- Male
- Pedigree
- Phenotype