Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prenatal diagnosis of X-linked hypohidrotic ectodermal dysplasia by linkage analysis.

American journal of medical genetics - 1 Jan 1990

Zonana J, Schinzel A, Upadhyaya M, Thomas N S, Anton-Lamprecht I, Harper P S

Abstract excerpt

Prenatal diagnosis of X-linked hypohidrotic ectodermal dysplasia was previously performed by the direct histological analysis of fetal skin obtained by late second trimester fetoscopy. The recent gene mapping of the locus for the disorder to the region of Xq11-21.1 now permits the indirect prenatal diagnosis of the disorder by the method of linkage analysis, based on closely linked marker loci, during the first...

Topics

Adult
Alleles
Chromosome Mapping
DNA
Ectodermal Dysplasia
Female
Genetic Linkage
Genetic Markers
Humans
Hypohidrosis
Pedigree
Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prenatal Diagnosis

X Chromosome

Source

Identifiers

PMID: 2301463
DOI: 10.1002/ajmg.1320350125

Genes

PGK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2301463-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prenatal diagnosis of X-linked hypohidrotic ectodermal dysplasia by linkage analysis.PMID 2301463Read ↗

Prenatal diagnosis of genodermatoses: current scope and future capabilitiesSemantic proximity Read ↗

Prenatal sonographic diagnosis of X-linked hypohidrotic ectodermal dysplasia: An unusual case.Semantic proximity Read ↗

The molecular genetics of the genodermatoses: progress to date and future directions.Semantic proximity Read ↗

Prenatal diagnosis of anhidrotic ectodermal dysplasia with unconventional loci abnormalities: a case report.Semantic proximity Read ↗

Prenatal Genetic Testing for X-Linked Hypohidrotic Ectodermal Dysplasia.Semantic proximity Read ↗

DNA-based prenatal diagnosis of heritable skin diseases.Semantic proximity Read ↗

Detection of de novo mutations and analysis of their origin in families with X linked hypohidrotic ectodermal dysplasia.Semantic proximity Read ↗

Pitfalls in clinical diagnosis of female carriers of X-linked hypohidrotic ectodermal dysplasia.Semantic proximity Read ↗

Prenatal diagnosis of factor X deficiency using a combination of direct mutation detection and linkage analysis with an intragenic single nucleotide polymorphism.Semantic proximity Read ↗

Genome-wide linkage analysis for hypospadias susceptibility genes.Semantic proximity Read ↗

Preimplantation genetic diagnosis of X-linked Charcot-Marie-Tooth disease by indirect linkage analysis.Semantic proximity Read ↗

Scarcity of mutations detected in families with X linked hypohidrotic ectodermal dysplasia: diagnostic implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.