Article
A case-control association study between the CYP3A4 and CYP3A5 genes and schizophrenia in the Chinese Han population.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Oct 2009
Du Jing, Xu Yifeng, Duan Shiwei, Zhang Aiping, Xuan Jiekun, Wang Lei, Yu Lan, Wang Hongsheng, Li Xingwang, Feng Guoyin, He Lin, Xing Qinghe
Abstract excerpt
In this study, variants of two genes coding for cytochrome P450 enzyme (CYP3A4 and CYP3A5) were analysed in a case-control sample using 398 schizophrenic patients and 391 healthy controls. All subjects were unrelated Han Chinese from Shanghai. No difference was observed on the allelic or genotypic distribution of CYP3A4 and CYP3A5 gene polymorphisms between the groups. However, the two-marker haplotypes covering...
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