Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.

The EMBO journal - 1 Sept 1992

Fuerstenberg S, Leitner I, Schroeder C, Schwarz H, Vennström B, Beug H

Abstract excerpt

The v-erbA oncogene confers two prominent properties on transformed erythroblasts: a block of spontaneous differentiation and tolerance to wide variations in the pH or ionic strength of culture medium. V-erbA acts as a constitutive repressor of erythrocyte-specific gene transcription, arresting the expression of at least three different erythroid genes: the erythrocyte anion transporter (band 3), carbonic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Cell Transformation, Neoplastic

Share to Cells, Cultured

Share to Fibroblasts

Share to Gene Expression Regulation, Neoplastic

Share to Genetic Vectors

Source

Open in PubMed Open full text

Identifiers

PMID: 1354613
DOI: 10.1002/j.1460-2075.1992.tb05414.x
PMCID: PMC556870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.PMID 1354613Read ↗

The carbonic anhydrase II gene, a gene regulated by thyroid hormone and erythropoietin, is repressed by the v-erbA oncogene in erythrocytic cells.Semantic proximity Read ↗

Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.Semantic proximity Read ↗

Phosphorylation of the v-erbA protein is required for its function as an oncogene.Semantic proximity Read ↗

Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repression.Semantic proximity Read ↗

Altered Na+/H+ exchanger isoform 1 activity in immortalized lymphoblasts from women with pre-eclampsia: evidence for an intermediate phenotype.Semantic proximity Read ↗

v-erbA acts on retinoic acid receptors in immature avian erythroid cells.Semantic proximity Read ↗

Epigenetic Regulation of Erythropoiesis: From Developmental Programs to Therapeutic TargetsSemantic proximity Read ↗

Targeted disruption of the murine erythroid band 3 gene results in spherocytosis and severe haemolytic anaemia despite a normal membrane skeleton.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.