Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.

doi:10.1002/j.1460-2075.1992.tb05414.x

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Article

Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.

The EMBO journal - 1 Sept 1992

Fuerstenberg S, Leitner I, Schroeder C, Schwarz H, Vennström B, Beug H

Abstract excerpt

The v-erbA oncogene confers two prominent properties on transformed erythroblasts: a block of spontaneous differentiation and tolerance to wide variations in the pH or ionic strength of culture medium. V-erbA acts as a constitutive repressor of erythrocyte-specific gene transcription, arresting t...

Topics

5-Aminolevulinate Synthetase
Alpharetrovirus
Animals
Anion Exchange Protein 1, Erythrocyte
Anion Transport Proteins
Base Sequence
Carbonic Anhydrases
Carrier Proteins
Cell Differentiation
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cells, Cultured
Chick Embryo

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Erythroblasts

Fibroblasts

Gene Expression Regulation, Neoplastic

Genetic Vectors

Hydrogen-Ion Concentration

Source

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Identifiers

PMID: 1354613
DOI: 10.1002/j.1460-2075.1992.tb05414.x
PMCID: PMC556870

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1354613-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.