The carbonic anhydrase II gene, a gene regulated by thyroid hormone and erythropoietin, is repressed by the v-erbA oncogene in erythrocytic cells.

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Article

The carbonic anhydrase II gene, a gene regulated by thyroid hormone and erythropoietin, is repressed by the v-erbA oncogene in erythrocytic cells.

The New biologist - 1 Mar 1990

Pain B, Melet F, Jurdic P, Samarut J

Abstract excerpt

The v-erbA oncogene encodes an altered form of the nuclear receptor of the thyroid hormone triiodothyronine (T3). This altered receptor is unable to bind T3, and blocks the differentiation of chicken erythrocyte progenitor cells. To identify the cellular target genes of v-ErbA in the transformed...

Topics

Animals
Carbonic Anhydrases
Chick Embryo
Drug Synergism
Erythrocytes
Erythropoietin
Gene Expression Regulation
Genes, Regulator
In Vitro Techniques
Kinetics
Mutation
Oncogenes
Transcription, Genetic
Transformation, Genetic
Triiodothyronine

Source

Open in PubMed

Identifiers

PMID: 2126201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2126201-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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