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Article

A new polymorphic site in the G6PD gene.

Human genetics - 1 Jul 1992

Beutler E, Westwood B, Sipe B

Abstract excerpt

A polymorphic restriction site has been found in intron 11 of the gene for glucose-6-phosphate dehydrogenase (G6PD). This site is produced by a T----C substitution 13 bp upstream of exon 12, producing an NlaIII restriction site. In various populations there was a strong association between a T at nt 1311 of the G6PD cDNA and the presence of the NlaIII restriction site. Among African Americans, however, the...

Topics

Base Sequence
Black People
DNA Mutational Analysis
Deoxyribonucleases, Type II Site-Specific
Ethnicity
Genes
Glucosephosphate Dehydrogenase
Humans
Molecular Sequence Data
Mutation
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

United States

Black or African American

Source

Identifiers

PMID: 1353051
DOI: 10.1007/BF00219170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1353051-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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