Article
Linkage disequilibrium of polymorphic sites in the G6PD gene in African populations and the origin of G6PD A-.
Gene geography : a computerized bulletin on human gene frequencies - 1 Jan 2000
Vulliamy T J, Othman A, Town M, Nathwani A, Falusi Y, Luzzatto L
Abstract excerpt
So far, four polymorphic sites are known to exist in the glucose 6-phosphate dehydrogenase (G6PD) gene of people of African origin: the mutation in G6PD A (which creates a FokI restriction enzyme site); the additional mutation in G6PD A- (which creates an NlaIII site); and two restriction fragmen...
Topics
- Africa
- Base Sequence
- Black People
- Blotting, Southern
- DNA
- Glucosephosphate Dehydrogenase
- Haplotypes
- Humans
- Linkage Disequilibrium
- Male
- Molecular Sequence Data
- Mutation