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Article

The origin of glucose-6-phosphate-dehydrogenase (G6PD) polymorphisms in African-Americans.

American journal of human genetics - 1 Feb 1992

Kay A C, Kuhl W, Prchal J, Beutler E

Abstract excerpt

DNA samples from 54 male Afro-Americans were examined for glucose-6-phosphate dehydrogenase (G6PD) genotypes G6PD A(+)376G, G6PD A(-)202A/376G, and G6PD B and for polymorphisms in intron 5 (PvuII), at nucleotide 1311, and at nucleotide 1116 (PstI). In the G6PD B subjects, the nucleotide 1311 mutation and the PstI site appeared to be in linkage equilibrium. No PvuII+ G6PD men were encountered. The G6PD A(+)...

Topics

Black People
Genetics, Population
Genotype
Glucosephosphate Dehydrogenase
Haplotypes
Humans
Linkage Disequilibrium
Male
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

United States

Black or African American

Source

Open in PubMed Open full text

Identifiers

PMID: 1734718
PMCID: PMC1682465

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1734718-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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