Article
Rapid detection of common Chinese glucose-6-phosphate dehydrogenase (G6PD) mutations by denaturing gradient gel electrophoresis (DGGE).
Genetic analysis : biomolecular engineering - 1 Mar 1996
Lam V M, Huang W, Lam S T, Yeung C Y, Johnson P H
Abstract excerpt
We describe here the use of denaturing gradient gel electrophoresis (DGGE) to detect the most common Chinese glucose-6-phosphate dehydrogenase (G6PD) variants, which are the single point mutations: G-->T at nt 1376, G-->A at 1388 both in exon 12 and A-->G at nt 95 in exon 02. In each case, the mu...
Topics
- Alleles
- Base Sequence
- China
- DNA Mutational Analysis
- DNA Primers
- Electrophoresis, Polyacrylamide Gel
- Exons
- Female
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Variation
- Glucosephosphate Dehydrogenase