Article
Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency by natural and amplification created restriction sites: five mutations account for most G6PD deficiency cases in Taiwan.
Blood - 15 Aug 1992
Chang J G, Chiou S S, Perng L I, Chen T C, Liu T C, Lee L S, Chen P H, Tang T K
Abstract excerpt
We have developed a rapid and simple method to diagnose the molecular defects of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Chinese in Taiwan. This method involves the selective amplification of a DNA fragment from human G6PD gene with specific oligonucleotide primers followed by dige...
Topics
- Base Sequence
- DNA
- DNA Restriction Enzymes
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Taiwan